An, SS ; Lim, KT ; Oh, HJ ; Lee, BS ; Zukic, E ; Ju, YR ; Yokoyama, T ; Kim, SY ; Welker, Ervin

Differentiating blood samples from scrapie infected and non-infected hamsters by detecting disease-associated prion proteins using Multimer Detection System.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 392 : 4 pp. 505-509. , 5 p. (2010)

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Article (Journal Article) 

Narayan, M ; Welker, Ervin ; Zhai, H ; Han, X ; Xu, G ; McLafferty, FW ; Scheraga, HA

Detecting native folds in mixtures of proteins that contain disulfide bonds

NATURE BIOTECHNOLOGY 26 pp. 427-429. , 3 p. (2008)

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Article (Journal Article)

Welker, Ervin ; Hathaway, L ; Narayan, M ; Pradeep, L ; Shin, HC ; Scheraga, HA

Oxidative folding and N-terminal cyclization of Onconase

BIOCHEMISTRY 46 : 18 pp. 5485-5493. , 9 p. (2007)

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Article (Journal Article)

Xu, GQ ; Narayan, M ; Kurinov, I ; Ripoll, DR ; Welker, Ervin ; Khalili, M ; Ealick, SE ; Scheraga, HA

A localized specific interaction alters the unfolding pathways of structural homologues

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 128 pp. 1204-1213. , 10 p. (2006)

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Article (Journal Article)

Zabrouskov, V ; Han, XM ; Welker, Ervin ; Zhai, HL ; Lin, C ; van Wijk, KJ ; Scheraga, HA ; McLafferty, FW

Stepwise deamidation of ribonuclease A at five sites determined by top down mass spectrometry

BIOCHEMISTRY 45 pp. 987-992. , 6 p. (2006)

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Article (Journal Article)

Mahesh Narayan ; Guoqiang Xu ; Daniel R Ripoll ; Huili Zhai ; Kathrin Breuker ; Celestine Wanjalla ; Howard J Leung ; Amiel Navon ; Ervin Welker ; Fred W McLafferty ; Harold A Scheraga

Dissimilarity in the reductive unfolding pathways of two ribonuclease homologues

JOURNAL OF MOLECULAR BIOLOGY 338 pp. 795-809. , 15 p. (2004)

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Article (Journal Article)

Welker, Ervin ; Maki, K ; Shastry, McR ; Juminaga, D ; Bhat, R ; Scheraga, HA ; Roder, H

Ultrarapid mixing experiments shed new light on the characteristics of the initial conformational ensemble during the folding of

ribonuclease A

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101 pp. 17681-17686. , 6 p. (2004)

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Article (Journal Article)

Welker, Ervin ; Hathaway, L ; Scheraga, HA

A new method for rapid characterization of the folding pathways of multidisulfide-containing proteins

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 126 pp. 3720-3721. , 2 p. (2004)

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Article (Journal Article)

Xu, GQ ; Narayan, M ; Welker, Ervin ; Scheraga, HA

Characterization of the fast-forming intermediate, des [30-75], in the reductive unfolding of onconase

BIOCHEMISTRY 43 pp. 3246-3254. , 9 p. (2004)

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Article (Journal Article)

Cerovsky, V ; Welker, Ervin ; Scheraga, HA

A convenient incorporation of conformationally constrained 5,5-dimethylproline into the ribonuclease A 89-124 sequence by condensation of synthetic peptide fragments

JOURNAL OF PEPTIDE RESEARCH 61 pp. 140-151. , 12 p. (2003)

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Article (Journal Article)

Narayan, M ; Welker, Ervin ; Scheraga, HA

Native conformational tendencies in unfolded polypeptides: Development of a novel method to assess native conformational tendencies in the reduced forms of multiple disulfide-bonded proteins

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125 pp. 2036-2037. , 2 p. (2003)

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Article (Journal Article)

Narayan, M ; Welker, Ervin ; Scheraga, HA

Characterizing the unstructured intermediates in oxidative folding

BIOCHEMISTRY 42 pp. 6947-6955. , 9 p. (2003)

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Article (Journal Article)

Narayan, M ; Welker, Ervin ; Wanjalla, C ; Xu, GQ ; Scheraga, HA

Shifting the competition between the intramolecular reshuffling reaction and the direct oxidation reaction during the oxidative folding of kinetically trapped disulfide-insecure intermediates

BIOCHEMISTRY 42 pp. 10783-10789. , 7 p. (2003)

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Article (Journal Article)

Xu, GQ ; Narayan, M ; Welker, Ervin ; Scheraga, HA

A novel method to determine thermal transition curves of disulfide-containing proteins and their structured folding intermediates

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 311 pp. 514-517. , 4 p. (2003)

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Article (Journal Article)

English, BP ; Welker, Ervin ; Narayan, M ; Scheraga, HA

Development of a novel method to populate native disulfide-bonded intermediates for structural characterization of proteins: Implications for the mechanism of oxidative folding of RNase A

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 124 pp. 4995-4999. , 5 p. (2002)

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Article (Journal Article)

Wedemeyer, WJ ; Xu, XB ; Welker, Ervin ; Scheraga, HA

Conformational propensities of protein folding intermediates: Distribution of species in the 1S, 2S, and 3S ensembles of the [C40A,C95A] mutant of bovine pancreatic ribonuclease A

BIOCHEMISTRY 41 pp. 1483-1491. , 9 p. (2002)

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Article (Journal Article)

Wedemeyer, WJ ; Welker, Ervin ; Scheraga, HA

Proline cis-trans isomerization and protein folding

BIOCHEMISTRY 41 pp. 14637-14644. , 8 p. (2002)

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Article (Journal Article)

Welker, Ervin ; Raymond, LD ; Scheraga, HA ; Caughey, B

Intramolecular versus intermolecular disulfide bonds in prion proteins

JOURNAL OF BIOLOGICAL CHEMISTRY 277 pp. 33477-33481. , 5 p. (2002)

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Article (Journal Article)

Cao, A ; Welker, Ervin ; Scheraga, HA

Effect of mutation of proline 93 on redox unfolding/folding of bovine pancreatic ribonuclease A

BIOCHEMISTRY 40 : 29 pp. 8536-8541. , 6 p. (2001)

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Article (Journal Article)

Narayan, M ; Welker, Ervin ; Scheraga, HA

Development of a novel method to study the rate-determining step during protein regeneration: Application to the oxidative folding of RNase A at low temperature reveals BPTI-like kinetic traps

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123 pp. 2909-2910. , 2 p. (2001)

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Article (Journal Article)

Saito, K ; Welker, Ervin ; Scheraga, HA

Folding of a disulfide-bonded protein species with free thiol(s): Competition between conformational folding and disulfide reshuffling in an intermediate of bovine pancreatic ribonuclease A

BIOCHEMISTRY 40 pp. 15002-15008. , 7 p. (2001)

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Article (Journal Article)

Scheraga, HA ; Wedemeyer, WJ ; Welker, Ervin

Bovine pancreatic ribonuclease A: Oxidative and conformational folding studies

METHODS IN ENZYMOLOGY 341 pp. 189-221. , 33 p. (2001)

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Article (Journal Article)

Welker, Ervin ; Narayan, M ; Wedemeyer, WJ ; Scheraga, HA

Structural determinants of oxidative folding in proteins

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 pp. 2312-2316. , 5 p. (2001)

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Article (Journal Article)

Welker, Ervin ; Wedemeyer, WJ ; Scheraga, HA

A role for intermolecular disulfide bonds in prion diseases?

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98 pp. 4334-4336. , 3 p. (2001)

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Article (Journal Article)

Welker, Ervin ; Wedemeyer, WJ ; Narayan, M ; Scheraga, HA

Coupling of conformational folding and disulfide-bond reactions in oxidative folding of proteins

BIOCHEMISTRY 40 : 31 pp. 9059-9064. , 6 p. (2001)

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Article (Journal Article)

Narayan, M ; Welker, Ervin ; Wedemeyer, WJ ; Scheraga, HA

Oxidative folding of proteins

ACCOUNTS OF CHEMICAL RESEARCH 33 pp. 805-812. , 8 p. (2000)

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Article (Journal Article)

Smith, AJ ; van Helvoort, A ; Van, Meer G ; Szabó, K ; Welker, Ervin ; Szakacs, G ; Varadi, A ; Sarkadi, B ; Borst, P

MDR3P-glycoprotein a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping

JOURNAL OF BIOLOGICAL CHEMISTRY 275 : 31 pp. 23530-23539. , 10 p. (2000)

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Article (Journal Article)

Wedemeyer, WJ ; Welker, Ervin ; Narayan, M ; Scheraga, HA

Disulfide bonds and protein folding

BIOCHEMISTRY 39 pp. 4207-4216. , 10 p. (2000)

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Article (Journal Article)

Welker, Ervin ; Váradi, András

Vectors with hidden cloning sites

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 271 : 2 pp. 534-536. , 3 p. (2000)

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Article (Journal Article)

An, Ssa ; Lester, CC ; Peng, JL ; Li, YJ ; Rothwarf, DM ; Welker, Ervin ; Thannhauser, TW ; Zhang, LS ; Tam, JP ; Scheraga, HA

Retention of the cis proline conformation in tripeptide fragments of bovine pancreatic ribonuclease A containing a non-natural proline analogue, 5,5-dimethylproline

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 121 pp. 11558-11566. , 9 p. (1999)

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Article (Journal Article)

Welker, Ervin ; Narayan, M ; Volles, MJ ; Scheraga, HA

Two new structured intermediates in the oxidative folding of RNase A

FEBS LETTERS 460 pp. 477-479. , 3 p. (1999)

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Article (Journal Article)

Welker, Ervin ; Scheraga, HA

Use of benzyl mercaptan for direct preparation of long polypeptidebenzylthio esters as substrates of subtiligase

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 254 pp. 147-151. , 5 p. (1999)

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Article (Journal Article)

Bakos, E ; Evers, R ; Szakács, G ; Tusnády, GE ; Welker, Ervin ; Szabó, K ; de Haas, M ; van Deemter, L ; Borst, P ; Váradi, A et al.

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

JOURNAL OF BIOLOGICAL CHEMISTRY 273 : 48 pp. 32167-32175. , 9 p. (1998)

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Article (Journal Article)

Szabó, K ; Welker, Ervin ; Bakos, É ; Müller, M ; Roninson, I ; Váradi, A ; Sarkadi, B

Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains

JOURNAL OF BIOLOGICAL CHEMISTRY 273 : 17 pp. 10132-10138. , 7 p. (1998)

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Article (Journal Article)

Bakos, E ; Klein, I ; Welker, Ervin ; Szabó, K ; Müller, M ; Sarkadi, B ; Váradi, A

Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region

BIOCHEMICAL JOURNAL 323 pp. 777-783. , 7 p. (1997)

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Article (Journal Article)

Szabó, K ; Bakos, E ; Welker, Ervin ; Müller, M ; Goodfellow, HR ; Higgins, CF ; Váradi, A ; Sarkadi, B

Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity

JOURNAL OF BIOLOGICAL CHEMISTRY 272 pp. 23165-23171. , 7 p. (1997)

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Article (Journal Article)

Bakos, E ; Hegedűs, T ; Holló, Z ; Welker, Ervin ; Tusnády, GE ; Zaman, GJ ; Flens, MJ ; Váradi, A ; Sarkadi, B

Membrane topology and glycosylation of the human multidrug resistance-associated protein

JOURNAL OF BIOLOGICAL CHEMISTRY 271 : 21 pp. 12322-12326. , 5 p. (1996)

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Article (Journal Article)

Müller, M ; Bakos, E ; Welker, Ervin ; Váradi, A ; Germann, UA ; Gottesman, MM ; Morse, BS ; Roninson, IB ; Sarkadi, B

Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

JOURNAL OF BIOLOGICAL CHEMISTRY 271 : 4 pp. 1877-1883. , 7 p. (1996)

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Article (Journal Article)

Welker, Ervin ; Szabó, K ; Holló, Z ; Müller, M ; Sarkadi, B ; Váradi, A

Drug-stimulated ATPase activity of a deletion mutant of the human multidrug-resistance protein (MDR1)

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 216 pp. 602-609. , 8 p. (1995)

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Article (Journal Article)