{"id":2061,"date":"2024-09-09T08:16:24","date_gmt":"2024-09-09T06:16:24","guid":{"rendered":"https:\/\/welkerlab.hu\/?page_id=2061"},"modified":"2024-09-13T09:53:03","modified_gmt":"2024-09-13T07:53:03","slug":"biczok-zsuzsanna","status":"publish","type":"page","link":"https:\/\/welkerlab.hu\/en\/biczok-zsuzsanna\/","title":{"rendered":"Zsuzsanna Bicz\u00f3k"},"content":{"rendered":"
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Zsuzsanna Bicz\u00f3k<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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PhD student<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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I am working to understand how a CRISPR-Cas9-based gene editing technique, prime editing, works in human cells. I am investigating the effects of the \ncomplementarities in the extended RNA used in this method, which could potentially reduce the efficiency of editing. I am also involved in the development of a prime editing-based method that allows efficient and accurate insertion of longer DNA sequences into the genome. This will allow the tagging of proteins without creating unwanted modifications in the coding gene and affecting the function of the gene.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Education<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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2021 - Present<\/em>
Doctoral school
Molecular Medicine<\/em>
<\/strong>Semmelweis University (SOTE)

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2018-2020<\/em>
Biology MSc
Molecular Genetics, Cell and Developmental Biology specialization<\/em>
<\/strong>E\u00f6tv\u00f6s Lor\u00e1nd University (ELTE)<\/p>

2015-2018<\/em>
Biology BSc
<\/strong>E\u00f6tv\u00f6s Lor\u00e1nd University (ELTE)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Research Interest<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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I am interested in the potential use of CRISPR and its variants in therapy. I would also like to expand my knowledge of new generation data evaluation methods and working with human pluripotent stem cells.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Simon, Dorottya Anna<\/a>\u00a0;\u00a0T\u00e1las, Andr\u00e1s<\/a>\u00a0;\u00a0Kulcs\u00e1r, P\u00e9ter Istv\u00e1n<\/a>\u00a0;\u00a0Bicz\u00f3k, Zsuzsanna<\/a>\u00a0<\/strong>;\u00a0Krausz, Sarah Laura<\/a>\u00a0;\u00a0V\u00e1rady, Gy\u00f6rgy<\/a>\u00a0;\u00a0Welker, Ervin<\/a>
PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully primed edited cells<\/a><\/em><\/span>
ELIFE 11 Paper: e69504, 19 p. (2022)
DOI\u00a0 \u00a0<\/a>WoS\u00a0 \u00a0<\/a>\u00a0REAL\u00a0 \u00a0<\/a>Scopus\u00a0 \u00a0<\/a>PubMed<\/a>
Article (Journal Article)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Bicz\u00f3k Zsuzsanna PhD-hallgat\u00f3 Egy CRISPR- Cas9 alap\u00fa g\u00e9nedit\u00e1l\u00e1si technika, a prime editing m\u0171k\u00f6d\u00e9s\u00e9nek meg\u00e9rt\u00e9s\u00e9vel foglalkozom hum\u00e1n sejtekben. Az itt haszn\u00e1lt meghosszabb\u00edtott RNS-ben el\u0151fordul\u00f3 komplementarit\u00e1sok a m\u00f3dszerre gyakorolt hat\u00e1sait vizsg\u00e1lom, amelyek potenci\u00e1lisan cs\u00f6kkenthetik az edit\u00e1l\u00e1si hat\u00e9konys\u00e1got. Emellett egy olyan prime editingen alapul\u00f3 m\u00f3dszer kifejleszt\u00e9s\u00e9ben veszek r\u00e9szt, amely lehet\u0151v\u00e9 teszi hosszabb DNS szakszok hat\u00e9kony \u00e9s pontos beilleszt\u00e9s\u00e9t […]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-2061","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/pages\/2061","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/comments?post=2061"}],"version-history":[{"count":19,"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/pages\/2061\/revisions"}],"predecessor-version":[{"id":2342,"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/pages\/2061\/revisions\/2342"}],"wp:attachment":[{"href":"https:\/\/welkerlab.hu\/en\/wp-json\/wp\/v2\/media?parent=2061"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}